The prognosis of pancreatic cancer is the worst of all common human cancer.

The prognosis of pancreatic cancer is the worst of all common human cancer. Chronic pancreatitis is a disease with limited therapeutic options in a significant proportion of patients, and is also a risk factor for pancreatic cancer. Inhibition of accompanying fibrosis could be a novel adjuvant approach to treat both diseases in the future if certain antifibrotic agent available.

In addition, studies showed on the regulation of ET – 1 synthesis that Transforming Growth Factor? 1 and tumor necrosis factor? strongly stimulate ET-1 secretion by PSC. Taken together, the results of the study of Jonitz et al. Suggest that ET-1 is part of a network of proinflammatory mediators and profibrogenic interactions between inflammatory cells and ultimately improve PSC promotes inflammation and fibrosis. The authors suggest that further experimental studies efficiency of efficiency of endothelin receptor antagonists in pancreatic fibrosis.. A team of researchers in the articles published in World Journal of Gastroenterology addresses this question. The results of the study of Jonitz et al. Insight into the effects of the extracellular mediator endothelin-1 in PSC.Younger who or mental health risk studyinhabitants out of rural areas, with an increased risk of mental health problems may be. If so, may public health programs prevent poor mental health to be adapted geared to a delivery for the rural areas. The purpose of this this study was the relation between residence in a rural region and frequent psychological stress , which to study an indicator of poor mental health.

MethodThe Behavioral Risk Factor Surveillance System topic to the state of Texas been the source of Details of obesity, demographic characteristics, and frequently psychological strain . Foot bad poor self-rated mental health of at least half the days over the last month. Adjusted odds on MCS rural and suburban respondent calculated in relation to urban those surveyed.